As we age, our laugh lines, the nasolabial folds, get more pronounced and make us look even older. We lose facial volume as our fat store are lost, further aging our appearance. To restore our youthful face, wrinkles must be smoothened, and volume and shape of our facial features must be restored. What if we could dramatically improve our facial appearance without surgery?
Radiesse is a dermal filler that is safe and effective, provides visible and long-term facial rejuvenation, and is indicated for the correction of moderate to severe wrinkles and folds and volumization of facial soft-tissue. Radiesse is a biodegradable filler consisting of 30% synthetic calcium hydroxylapatite (CaHA) microspheres (diameter of 25-45μm) suspended in a 70% aqueous carboxymethylcellulose gel carrier. The microspheres induce new collagen formation by fibroblast activation. Collagen provides structural integrity and improvement of dermal appearance. CaHA is naturally found in human bone and dental enamel, and is very biocompatible and so doesn’t require skin testing.
A large amount of research and a recent clinical study shows that Radiesse significantly stimulates collagen production over many months of follow-up. Radiesse can provide both immediate replacement volume and long-term (collagen biostimulation) volume enhancement. A study comprising 4 centers enrolled 117 subjects with moderate to deep nasolabial folds. Subjects received CaHA on one side of the face and human collagen on the other. Experts evaluated subject photographs from initial and follow-up visits, and didn’t know which side received the Radiesse or the collagen. Radiesse was found to be superior to collagen in 79% of the folds after 6 months, and significantly less volume and fewer injections were needed for CaHA than for collagen. Adverse event rates were comparable, as were adverse event duration, and generally resolved within 14 to 21 days. This CaHA-based product gives longer-lasting correction of nasolabial folds compared to collagen. Results typically last for 12-18 months, and evidence shows that retreatment with Radiesse between six and 12 months produced improvement that was still observed in 40% of the folds at 30 months following the last treatment with Radiesse.
Comparing Radiesse with collagen injections, we note that Radiesse produces superior improvement of the appearance of nasolabial folds.
The results of several studies suggest a very favorable safety profile with a very high patient satisfaction rating, and over 90% indicated that their results were “good” or “very good” according to a multicenter, 47-month study of Radiesse.
The Radiesse CaHA microspheres are inert and nonantigenic. Adverse events are generally mild, and include bruising, edema, erythema, pain, and pruritus, and are short in duration.
Results will depend on the patient’s look before treatment and on their expectations, but a pre-injection consultation will Dr. Gafanovich will provide you with an honest evaluation of your condition.
Radiesse is appropriate at any stage of the aging process and a recent study describes it as a “very effective agent for many areas of facial soft tissue augmentation and is associated with a high and well-established safety profile. Calcium hydroxylapatite combines high elasticity and viscosity with an ability to induce long-term collagen formation making it an ideal agent for a global facial approach.”